Drohat, A. C.: search on Z-Library

The world's largest scientific articles store. 70,000,000+ articles for free.

Don't use scam websites

1

Crystal structure of Escherichia coli uracil DNA glycosylase and its complexes with uracil and glycerol: Structure and glycosylase mechanism revisited

Gaoyi Xiao, Maria Tordova, Jaya Jagadeesh, Alexander C. Drohat, James T. Stivers, Gary L. Gilliland

Journal:

Proteins: Structure, Function, and Bioinformatics

Year:

1999

Language:

english

File:

PDF, 1.20 MB

english, 1999

2

Structural Studies of RNA/DNA Polypurine Tracts

Megan E. Fitzgerald, Alexander C. Drohat

Journal:

Chemistry & Biology

Year:

2008

Language:

english

File:

PDF, 136 KB

english, 2008

3

Oligomerization state of S100B at nanomolar concentration determined by large-zone analytical gel filtration chromatography

Alexander C. Drohat, David J. Weber, Elizabeth Nenortas, Dorothy Beckett

Journal:

Protein Science

Year:

1997

Language:

english

File:

PDF, 2.50 MB

english, 1997

4

S100B(ββ) inhibits the protein kinase C-dependent phosphorylation of a peptide derived from p53 in a Ca2+-dependent manner

Paul T. Wilder, Richard R. Rustandi, Alexander C. Drohat, David J. Weber

Journal:

Protein Science

Year:

1998

Language:

english

File:

PDF, 509 KB

english, 1998

5

Chemical shift assignments for human apurinic/apyrimidinic endonuclease 1

Brittney A. Manvilla, Kristen M. Varney, Alexander C. Drohat

Journal:

Biomolecular NMR Assignments

Year:

2010

Language:

english

File:

PDF, 669 KB

english, 2010

6

3-methyladenine DNA glycosylase I is an unexpected helix-hairpin-helix superfamily member

Drohat, Alexander C., Kwon, Keehwan, Krosky, Daniel J., Stivers, James T.

Journal:

Natural Structural Biology

Year:

2002

Language:

english

File:

PDF, 799 KB

english, 2002

7

The use of dipolar couplings for determining the solution structure of rat apo-S100B(ββ)

Alexander C. Drohat, Nico Tjandra, Donna M. Baldisseri, David J. Weber

Journal:

Protein Science

Year:

1999

Language:

english

File:

PDF, 1.05 MB

english, 1999

8

Structural changes in the C-terminus of Ca2+-bound rat S100B(ββ) upon binding to a peptide derived from the C-terminal regulatory domain of p53

Richard R. Rustandi, Donna M. Baldisseri, Alexander C. Drohat, David J. Weber

Journal:

Protein Science

Year:

1999

Language:

english

File:

PDF, 590 KB

english, 1999

9

Dependence of substrate binding and catalysis on pH, ionic strength, and temperature for thymine DNA glycosylase: Insights into recognition and processing of G·T mispairs

Atanu Maiti, Alexander C. Drohat

Journal:

Year:

2011

Language:

english

File:

PDF, 723 KB

english, 2011

10

The role of cysteine residues in S100B dimerization and regulation of target protein activity

Aimee Landar, Tonya L Hall, Emily H Cornwall, John J Correia, Alexander C Drohat, David J Weber, Danna B Zimmer

Journal:

Biochimica et Biophysica Acta (BBA) - Protein Structure and Molecular Enzymology

Year:

1997

Language:

english

File:

PDF, 399 KB

english, 1997

11

Uracil DNA Glycosylase: Insights from a Master Catalyst

James T. Stivers, Alexander C. Drohat

Journal:

Archives of Biochemistry and Biophysics

Year:

2001

Language:

english

File:

PDF, 360 KB

english, 2001

12

Crystal Structure of Human Methyl-Binding Domain IV Glycosylase Bound to Abasic DNA

Brittney A. Manvilla, Atanu Maiti, Matthew C. Begley, Eric A. Toth, Alexander C. Drohat

Journal:

Journal of Molecular Biology

Year:

2012

Language:

english

File:

PDF, 1.40 MB

english, 2012

13

NMR Studies Reveal an Unexpected Binding Site for a Redox Inhibitor of AP Endonuclease 1

Manvilla, Brittney A., Wauchope, Orrette, Seley-Radtke, Katherine L., Drohat, Alexander C.

Journal:

Year:

2011

Language:

english

File:

PDF, 4.10 MB

english, 2011

14

Divergent Mechanisms for Enzymatic Excision of 5-Formylcytosine and 5-Carboxylcytosine from DNA

Maiti, Atanu, Michelson, Anna Zhachkina, Armwood, Cherece J., Lee, Jeehiun K., Drohat, Alexander C.

Journal:

Journal of the American Chemical Society

Year:

2013

Language:

english

File:

PDF, 2.33 MB

english, 2013

15

E2-mediated Small Ubiquitin-like Modifier (SUMO) Modification of Thymine DNA Glycosylase Is Efficient but Not Selective for the Enzyme-Product Complex

Coey, C. T., Fitzgerald, M. E., Maiti, A., Reiter, K. H., Guzzo, C. M., Matunis, M. J., Drohat, A. C.

Journal:

Journal of Biological Chemistry

Year:

2014

Language:

english

File:

PDF, 2.39 MB

english, 2014

16

The Ca 2+ -Dependent Interaction of S100B(ββ) with a Peptide Derived from p53 †

Rustandi, Richard R., Drohat, Alexander C., Baldisseri, Donna M., Wilder, Paul T., Weber, David J.

Journal:

Year:

1998

Language:

english

File:

PDF, 181 KB

english, 1998

17

Raman Spectroscopy of Uracil DNA Glycosylase−DNA Complexes: Insights into DNA Damage Recognition and Catalysis †

Dong, Jian, Drohat, Alexander C., Stivers, James T., Pankiewicz, Kryzsztof W., Carey, Paul R.

Journal:

Year:

2000

Language:

english

File:

PDF, 166 KB

english, 2000

18

NMR Evidence for an Unusually Low N1 p K a for Uracil Bound to Uracil DNA Glycosylase: Implications for Catalysis

Drohat, Alexander C., Stivers, James T.

Journal:

Journal of the American Chemical Society

Year:

2000

Language:

english

File:

PDF, 62 KB

english, 2000

19

Escherichia coli Uracil DNA Glycosylase: NMR Characterization of the Short Hydrogen Bond from His187 to Uracil O2 †

Drohat, Alexander C., Stivers, James T.

Journal:

Year:

2000

Language:

english

File:

PDF, 152 KB

english, 2000

20

Solution Structure of Calcium-Bound Rat S100B(ββ) As Determined by Nuclear Magnetic Resonance Spectroscopy †,‡

Drohat, Alexander C., Baldisseri, Donna M., Rustandi, Richard R., Weber, David J.

Journal:

Year:

1998

Language:

english

File:

PDF, 179 KB

english, 1998

21

Heteronuclear NMR and Crystallographic Studies of Wild-Type and H187Q Escherichia coli Uracil DNA Glycosylase: Electrophilic Catalysis of Uracil Expulsion by a Neutral Histidine 187 †

Drohat, Alexander C., Xiao, Gaoyi, Tordova, Maria, Jagadeesh, Jaya, Pankiewicz, Krzysztof W., Watanabe, Kyoichi A., Gilliland, Gary L., Stivers, James T.

Journal:

Year:

1999

Language:

english

File:

PDF, 245 KB

english, 1999

22

Solution Structure of Rat Apo-S100B(ββ) As Determined by NMR Spectroscopy †,‡

Drohat, Alexander C., Amburgey, Judith C., Abildgaard, Frits, Starich, Mary R., Baldisseri, Donna, Weber, David J.

Journal:

Year:

1996

Language:

english

File:

PDF, 752 KB

english, 1996

23

Mechanisms for enzymatic cleavage of the N-glycosidic bond in DNA

Drohat, Alexander C., Maiti, Atanu

Journal:

Organic & Biomolecular Chemistry

Year:

2014

Language:

english

File:

PDF, 1.16 MB

english, 2014

24

Role of Electrophilic and General Base Catalysis in the Mechanism of Escherichia coli Uracil DNA Glycosylase †

Drohat, Alexander C., Jagadeesh, Jayashree, Ferguson, Eric, Stivers, James T.

Journal:

Year:

1999

Language:

english

File:

PDF, 130 KB

english, 1999

25

Thymine DNA Glycosylase Can Rapidly Excise 5-Formylcytosine and 5-Carboxylcytosine: POTENTIAL IMPLICATIONS FOR ACTIVE DEMETHYLATION OF CpG SITES

Maiti, A., Drohat, A. C.

Journal:

Journal of Biological Chemistry

Year:

2011

Language:

english

File:

PDF, 1.07 MB

english, 2011

26

Excision of 5-Halogenated Uracils by Human Thymine DNA Glycosylase: ROBUST ACTIVITY FOR DNA CONTEXTS OTHER THAN CpG

Morgan, M. T., Bennett, M. T., Drohat, A. C.

Journal:

Journal of Biological Chemistry

Year:

2007

Language:

english

File:

PDF, 389 KB

english, 2007

27

Role of Two Strictly Conserved Residues in Nucleotide Flipping and N-Glycosylic Bond Cleavage by Human Thymine DNA Glycosylase

Maiti, A., Morgan, M. T., Drohat, A. C.

Journal:

Journal of Biological Chemistry

Year:

2009

Language:

english

File:

PDF, 1.93 MB

english, 2009

28

Coordinating the Initial Steps of Base Excision Repair: APURINIC/APYRIMIDINIC ENDONUCLEASE 1 ACTIVELY STIMULATES THYMINE DNA GLYCOSYLASE BY DISRUPTING THE PRODUCT COMPLEX

Fitzgerald, M. E., Drohat, A. C.

Journal:

Journal of Biological Chemistry

Year:

2008

Language:

english

File:

PDF, 982 KB

english, 2008

29

Lesion processing by a repair enzyme is severely curtailed by residues needed to prevent aberrant activity on undamaged DNA

Maiti, A., Noon, M. S., MacKerell, A. D., Pozharski, E., Drohat, A. C.

Journal:

Proceedings of the National Academy of Sciences

Year:

2012

Language:

english

File:

PDF, 865 KB

english, 2012

30

Crystal structure of human thymine DNA glycosylase bound to DNA elucidates sequence-specific mismatch recognition

Maiti, Atanu, Morgan, Michael T., Pozharski, Edwin, Drohat, Alexander C.

Journal:

Proceedings of the National Academy of Sciences

Year:

2008

Language:

english

File:

PDF, 1.31 MB

english, 2008

31

Solution Structure and Base Perturbation Studies Reveal a Novel Mode of Alkylated Base Recognition by 3-Methyladenine DNA Glycosylase I

Cao, Chunyang, Kwon, Keehwan, Jiang, Yu Lin, Drohat, Alexander C., Stivers, James T.

Journal:

Journal of Biological Chemistry

Year:

2003

Language:

english

File:

PDF, 928 KB

english, 2003

32

Structure of human apurinic/apyrimidinic endonuclease 1 with the essential Mg 2+ cofactor

Manvilla, Brittney A., Pozharski, Edwin, Toth, Eric A., Drohat, Alexander C.

Journal:

Acta Crystallographica Section D Biological Crystallography

Year:

2013

Language:

english

File:

PDF, 7.66 MB

english, 2013

33

Role of base excision repair in maintaining the genetic and epigenetic integrity of CpG sites

Bellacosa, Alfonso, Drohat, Alexander C.

Journal:

Year:

2015

Language:

english

File:

PDF, 2.47 MB

english, 2015

34

The human checkpoint sensor Rad9 Rad1 Hus1 interacts with and stimulates DNA repair enzyme TDG glycosylase

Guan, X., Madabushi, A., Chang, D.-Y., Fitzgerald, M. E., Shi, G., Drohat, A. C., Lu, A-L.

Journal:

Nucleic Acids Research

Year:

2007

Language:

english

File:

PDF, 576 KB

english, 2007

35

Thymine DNA glycosylase exhibits negligible affinity for nucleobases that it removes from DNA

Malik, Shuja S., Coey, Christopher T., Varney, Kristen M., Pozharski, Edwin, Drohat, Alexander C.

Journal:

Nucleic Acids Research

Year:

2015

Language:

english

File:

PDF, 9.38 MB

english, 2015

36

How a mismatch repair enzyme balances the needs for efficient lesion processing and minimal action on undamaged DNA

Drohat, Alexander C., Pozharski, Edwin, Maiti, Atanu

Journal:

Year:

2012

Language:

english

File:

PDF, 336 KB

english, 2012

37

Lesion search and recognition by thymine DNA glycosylase revealed by single molecule imaging

Buechner, C. N., Maiti, A., Drohat, A. C., Tessmer, I.

Journal:

Nucleic Acids Research

Year:

2015

Language:

english

File:

PDF, 1.67 MB

english, 2015

38

Characterizing Requirements for SUMO Modification and Binding on Base Excision Repair Activity of Thymine DNA Glycosylase in Vivo

McLaughlin, Dylan, Coey, Christopher T., Yang, Wei-Chih, Drohat, Alexander C., Matunis, Michael J.

Journal:

Journal of Biological Chemistry

Year:

2016

Language:

english

File:

PDF, 1.75 MB

english, 2016

39

Specificity of Human Thymine DNA Glycosylase Depends on N -Glycosidic Bond Stability

Bennett, Matthew T., Rodgers, M. T., Hebert, Alexander S., Ruslander, Lindsay E., Eisele, Leslie, Drohat, Alexander C.

Journal:

Journal of the American Chemical Society

Year:

2006

Language:

english

File:

PDF, 218 KB

english, 2006

40

ChemInform Abstract: Mechanisms for Enzymatic Cleavage of the N-Glycosidic Bond in DNA

Drohat, Alexander C., Maiti, Atanu

Journal:

Year:

2014

File:

PDF, 12 KB

2014

41

Role of Base Excision “Repair” Enzymes in Erasing Epigenetic Marks from DNA

Drohat, Alexander C., Coey, Christopher T.

Journal:

Chemical Reviews

Year:

2016

Language:

english

File:

PDF, 4.55 MB

english, 2016

42

Replication-Dependent Unhooking of DNA Interstrand Cross-Links by the NEIL3 Glycosylase

Semlow, Daniel R., Zhang, Jieqiong, Budzowska, Magda, Drohat, Alexander C., Walter, Johannes C.

Journal:

Year:

2016

Language:

english

File:

PDF, 6.69 MB

english, 2016

43

Structural basis of damage recognition by thymine DNA glycosylase: Key roles for N-terminal residues

Coey, Christopher T., Malik, Shuja S., Pidugu, Lakshmi S., Varney, Kristen M., Pozharski, Edwin, Drohat, Alexander C.

Journal:

Nucleic Acids Research

Year:

2016

Language:

english

File:

PDF, 2.81 MB

english, 2016

44

Structural Basis for Excision of 5-Formylcytosine by Thymine DNA Glycosylase

Pidugu, Lakshmi S., Flowers, Joshua W., Coey, Christopher T., Pozharski, Edwin, Greenberg, Marc M., Drohat, Alexander C.

Journal:

Year:

2016

Language:

english

File:

PDF, 2.21 MB

english, 2016

45

Defining the impact of sumoylation on substrate binding and catalysis by thymine DNA glycosylase

Coey, Christopher T, Drohat, Alexander C

Journal:

Nucleic Acids Research

Year:

2018

Language:

english

File:

PDF, 2.23 MB

english, 2018

46

Nucleosomes and the three glycosylases: High, medium, and low levels of excision by the uracil DNA glycosylase superfamily

Tarantino, Mary E., Dow, Blaine J., Drohat, Alexander C., Delaney, Sarah

Journal:

Year:

2018

Language:

english

File:

PDF, 933 KB

english, 2018

47

Molecular Dynamics Simulation Study of DNA Mismatch Recognition by Complementary Strand Interactions in Thymine DNA Glycosylase

Yoluk, Ozge, Drohat, Alexander C., MacKerell, Alexander D.

Journal:

Biophysical Journal

Year:

2018

Language:

english

File:

PDF, 66 KB

english, 2018

48

Defining the Role of Nucleotide Flipping in Enzyme Specificity using 19F NMR

Dow, Blaine J, Malik, Shuja Shafi, Drohat, Alexander C

Journal:

Journal of the American Chemical Society

Year:

2019

Language:

english

File:

PDF, 566 KB

english, 2019

49

Elucidating Complimentary Base Specificity of Thymine DNA Glycosylase via Potential of Mean Force Molecular Dynamics Simulations

Yoluk, Ozge, Drohat, Alexander C., MacKerell, Alexander D.

Journal:

Biophysical Journal

Year:

2019

Language:

english

File:

PDF, 63 KB

english, 2019

50

Excision of 5-carboxylcytosine by Thymine DNA Glycosylase

Pidugu, Lakshmi S., Dai, Qing, Malik, Shuja Shafi, Pozharski, Edwin, Drohat, Alexander C

Journal:

Journal of the American Chemical Society

Year:

2019

Language:

english

File:

PDF, 939 KB

english, 2019